High Dose Vitamin C

An immune-boosting vitamin, Vitamin C has virtually no toxicity and has been taken long term as a complementary treatment to both the standard protocol and alternative treatments, including some listed here.

And while the amount one takes might sound extraordinarily high, the dosage levels have been proven safe in over 50 years of clinical use.

  • Resources
  • Active Clinical Trials (1)
  • Studies

Taking high doses of vitamins intravenously is becoming more mainstream; and in turn, offered by a wider variety of healthcare professionals.

Though there are oncologists offering it as a treatment and we do recommend working with one of them to ensure the proper dosing protocol is followed. 

Title: A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme

Link: https://clinicaltrials.gov/ct2/show/NCT02344355

Inclusion criteria: Newly diagnosed


  • Holden Comprehensive Cancer Center

Iowa City, Iowa, United States, 52242

Contact: Sandy Vollstedt, RN, BSN     319-353-7143     sandy-vollstedt@uiowa.edu

Principle Investigator: Bryan G. Allen, MD, PhD

Treatment Protocol: To be administered alongside the standard chemotherapy and radiation protocol.

Title: The Use of Intravenous Vitamin C as a Supportive Therapy for a Patient With Glioblastoma Multiforme

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162462/

Summary: This study tracked the progress of one patient that used High Dose Vitamin C regularly for four-plus years shortly thereafter being diagnosed.

Key takeaways:

  • Doctors believe it contributed to a higher quality of life and longer life expectancy
  • There were no adverse side effects when taken in conjunction with chemotherapy and radiation



Title: Systematic Review of Intravenous Ascorbate in Cancer Clinical Trials

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071214/

Summary: From 2018, this study reviewed the data regarding High Dose Vitamin C and cancer to date and found it to be a promising treatment that warrants further study.

Key takeaways:

  • Patients taking it experienced little to no toxicity
  • It is safe both as a standalone treatment and in conjunction with chemotherapy
  • It is found to generally improve quality of life
  • There is evidence that it leads to tumor regression and improved survival outcomes

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