The Ketogenic Diet

A ketogenic diet can put the body in an ideal state to prevent more cancer growth and provide it with cancer-fighting compounds – ketones. 

  • Resources
  • Active Clinical Trials (3)
  • Studies
Organizations:

The Charlie Foundation - a non-profit dedicated to implementing the spread of a ketogenic diet in clinical settings

Keto-Mojo - an organization providing tools and resources for the implementation of a keto diet

Books, for in-depth exploration:
Apps to food track with:

These are helpful when starting out as they can provide information as to which foods will help maintain ketosis

Cronometer

Cronometer is designed to track what is eaten throughout the day.

https://docs.google.com/spreadsheets/d/1mwdo5uKpj04-3htm-iSTv790btiMzJPDZ8waxa-jVkI/edit

This spreadsheet-based calculator shows if a particular food or meal will meet the desired ketogenic macronutrient profile.

Exogenous ketones:

It is also possible to supplement ketones in order to increase what the body is already producing.

In limited trials, they have been shown to support brain cancer patients as well.

Here are two studies demonstrating so:

Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy

The Contribution of Ketone Bodies to Glycolytic Inhibition for the Treatment of Adult and Pediatric Glioblastoma

Title: Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma

Link: https://clinicaltrials.gov/ct2/show/NCT03451799

Locations:

  • Cedars Sinai Medical Center

Los Angeles, California, United States, 90048

Contact: Amelia Welborn 310-248-8654     amelia.welborn@cshs.org  

Contact: Laura Lockshon 424-315-2219     laura.lockshon@cshs.org  

Principal Investigator: Jethro Hu, MD

Inclusion criteria: Newly Diagnosed

Treatment Protocol: Patients will implement the diet alongside the standard chemotherapy and radiation protocol.

 


 

Title: Feasibility Study of Modified Atkins Ketogenic Diet in the Treatment of Newly Diagnosed Malignant Glioma

Link: https://clinicaltrials.gov/ct2/show/NCT03278249

Locations:

  • UC Health

Cincinnati, Ohio, United States, 45219

Contact: University of Cincinnati Cancer Institute    513-584-7698    cancer@uchealth.com

Inclusion criteria: Newly Diagnosed

Treatment Protocol: Patients will implement a modified ketogenic diet alongside the standard chemotherapy and radiation protocol.

 


 

Title: Restricted Calorie Ketogenic Diet as a Treatment in Malignant Tumors

Link: https://clinicaltrials.gov/ct2/show/NCT03160599

Locations:

  • the Second Affiliated Hospital of Guangzhou Medical University

Guangzhou, Guangdong, China

Contact: Qian Chen    86 20 81340031

Inclusion criteria: Recurrence of disease

Treatment Protocol: Patients will implement a restricted ketogenic diet as the primary/standalone treatment.

Title: Role of ketogenic metabolic therapy in malignant glioma: A systematic review

Link: https://pubmed.ncbi.nlm.nih.gov/28325264/

Summary: From 2017, a study where scientists reviewed the current studies regarding the ketogenic diet and brain cancer and recognize it as an emerging treatment.

Key takeaways:

  • It is safe and feasible
  • Studies did demonstrate a benefit to patients

 


 

Title: Management of Glioblastoma Multiforme in a Patient Treated With Ketogenic Metabolic Therapy and Modified Standard of Care: A 24-Month Follow-Up

Link: https://pubmed.ncbi.nlm.nih.gov/29651419/

Summary: A study that tracked one patient who implemented a ketogenic diet and a number of adjunctive treatments that are listed in the abstract alongside the traditional chemotherapy and radiation protocol to much success.

Key takeaways:

  • 24 months into the protocol, the patient is in “excellent condition”
  • Tumor regression remains evident

 


 

Title: Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report

Link: https://pubmed.ncbi.nlm.nih.gov/20412570/

Summary: A study that tracked one patient implementing a ketogenic diet immediately upon diagnosis of GBM.

Key takeaways:

  • No tumor was detected two months after the implementation of a restricted ketogenic diet
  • Upon stopping the diet, the tumor did return

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